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abstractIt is generally agreed at international level that invasive prenatal diagnosis should be restricted to those women who are at a high risk of chromosome or gene pathologies. This is due to the high costs involved, the specificity of the diagnostic and sample-taking procedures, and the risk of abortion or complications related to obstetric procedures.
Extending the criteria for prenatal diagnosis beyond those recommended is contrary to economic sustainability, but above all to good clinical practice. Before resorting to invasive prenatal diagnosis, the doctor can put the patient through non-invasive, indirect screening, by combining the results of maternal serum markers with ultra-sound characteristics of the foetus and the gestational age. |
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