Riviste scientifiche

[Correspondence] Harmful marketing to children – Authors' reply

The Lancet - Sa, 28/11/2020 - 00:00
We thank Darren Powell for his insightful feedback. Members of the WHO–UNICEF–Lancet Commission1 agree with Powell that marketing of any products to children might encourage potentially harmful consumption for the child, the planet, and children's futures, and that more work in both academic and political spheres is needed to highlight the risks.1 Our Commission's analysis of children's wellbeing and rights extends to the dangers of the commercialisation of childhood.

[Correspondence] Ruxolitinib cream for the treatment of vitiligo

The Lancet - Sa, 28/11/2020 - 00:00
We read with interest the study by David Rosmarin and colleagues,1 which investigated the safety and efficacy of ruxolitinib cream in vitiligo. The study concluded that ruxolitinib cream is safe and effective as monotherapy in treating patients with vitiligo.1 We believe that this generalised statement cannot be concluded based on major study limitations.

[Correspondence] Ruxolitinib cream for the treatment of vitiligo – Authors' reply

The Lancet - Sa, 28/11/2020 - 00:00
We thank Shelley Uppal and colleagues for their comments on the randomised phase 2 trial of ruxolitinib cream for the treatment of vitiligo,1 in which concerns over the generalisability of the study population were raised. As a phase 2 study, the goal was to evaluate the efficacy and safety of different concentrations and dosing regimens of ruxolitinib cream in patients with non-segmental vitiligo before progressing to phase 3 studies, in which generalisability would be assessed. As such, our study1 does not state that ruxolitinib cream is a safe and effective treatment for vitiligo or conclude that the study's findings should extend to clinical practice.

[Department of Error] Department of Error

The Lancet - Sa, 28/11/2020 - 00:00
NCD Countdown 2030 collaborators. NCD Countdown 2030: pathways to achieving Sustainable Development Goal target 3.4. Lancet 2020; 396: 918–34—In this Health Policy paper, the list of collaborators was not supplied to PubMed. This correction has been made as of Nov 26, 2020.

[Department of Error] Department of Error

The Lancet - Sa, 28/11/2020 - 00:00
Burki T. Prince Mahidol award winners announced. Lancet 2020; 396: 1548–49—In this World Report, there was a typo in a quote given by Bernard Pécoul. It should have read: “Fexinidazole is a 10-day long course; we are hoping to be able to launch single-dose treatments for sleeping sickness sometime in the next few years.” This correction has been made to the online version as of Nov 26, 2020.

[Articles] First human facial retransplantation: 30-month follow-up

The Lancet - Sa, 28/11/2020 - 00:00
This clinical report of the first documented human facial retransplantation is proof-of-concept that the loss of a facial transplant after CAMR can be mitigated successfully by retransplantation combined with an aggressive desensitisation process.

[Clinical Picture] A disease disregards anatomical planes: actinomycosis and an intrauterine device

The Lancet - Sa, 28/11/2020 - 00:00
A 24-year-old woman was referred to our specialist unit with a 3-month history of 15·8 kg weight loss, increasing abdominal pain and bloating, fatigue, night sweats, difficulty passing urine, amenorrhoea, and trouble walking. She was nulligravida and had a copper intrauterine device (IUD) in situ for the past 4 years. She was a non-smoker, drank alcohol socially, and had no history of recent travel. She stated she was allergic to penicillin.

[Therapeutics] Direct oral anticoagulants: evidence and unresolved issues

The Lancet - Sa, 28/11/2020 - 00:00
Currently licenced direct oral anticoagulants selectively target thrombin (eg, dabigatran) or coagulation factor Xa (eg, apixaban, betrixaban, edoxaban, and rivaroxaban). Designed to be given in fixed doses without routine monitoring, direct oral anticoagulants have a lower propensity for food and drug interactions than do vitamin K antagonists, and in randomised controlled trials involving around 250 000 patients, they were at least as effective for prevention and treatment of thrombosis and were associated with a lower risk of life-threatening bleeding.

Covid-19 news: UK R number below 1.0 for the first time since August

New Scientist - Ve, 27/11/2020 - 17:59
The latest coronavirus news updated every day including coronavirus cases, the latest news, features and interviews from New Scientist and essential information about the covid-19 pandemic

AI can turn spoken language into photorealistic sign language videos

New Scientist - Ve, 27/11/2020 - 16:00
An AI that can produce photorealistic videos of sign language interpreters from speech could improve accessibility by removing the need for humans

We seem to find larger animals more charismatic than small ones

New Scientist - Ve, 27/11/2020 - 14:00
Survey data on human attitudes to 13,680 animal species suggests we judge larger animals as more charismatic – although some very small species are also seen as charismatic

Do Oxford/AstraZeneca covid-19 vaccine results stand up to scrutiny?

New Scientist - Ve, 27/11/2020 - 13:15
Doubts have been raised over the positive results released earlier this week by AstraZeneca and the University of Oxford from trials of their coronavirus vaccine. Here's what you need to know

Godzilla Sahara dust storm linked to melting Arctic sea ice

New Scientist - Ve, 27/11/2020 - 12:43
A record-breaking Sahara dust storm that spread harmful air pollution across parts of North America in June 2020 was caused by winds linked to melting Arctic sea ice

Google Earth reveals suspected nuclear weapons facility in Pakistan

New Scientist - Ve, 27/11/2020 - 10:55
Sleuthing with satellite images has revealed a substantial and undocumented expansion to a suspected nuclear processing plant in Pakistan, a possible sign the country is boosting capacity for its nuclear weapons programme

The dazzling winners of the British Ecological Society’s photo awards

New Scientist - Ve, 27/11/2020 - 02:00
Images of the extraordinary, but endangered, Dalmatian pelican and weaver ants caring for their young are among those awarded in this year's British Ecological Society’s "Capturing Ecology" photography competition

CRISPR gene editing of brain cells might prevent Alzheimer's disease

New Scientist - Gi, 26/11/2020 - 21:00
CRISPR gene editing could be used to introduce a rare gene variant that greatly reduces the risk of Alzheimer's, but it has only been tried in a dish so far

Climate change may make autumn leaves fall early and store less carbon

New Scientist - Gi, 26/11/2020 - 20:00
Tree leaves could start falling earlier in autumn due to climate change. The finding suggests forests will store significantly less carbon than expected as temperatures rise

Covid-19 news: New tiers announced for England after lockdown ends

New Scientist - Gi, 26/11/2020 - 18:13
The latest coronavirus news updated every day including coronavirus cases, the latest news, features and interviews from New Scientist and essential information about the covid-19 pandemic

NASA can't decide whether astronauts should wash their underwear

New Scientist - Gi, 26/11/2020 - 16:55
NASA has partnered with consumer goods firm Procter & Gamble to develop a detergent that can wash clothes in space. Up until now, NASA has found it more cost-efficient to dispose of dirty garments

Double climate disaster may have ended ancient Harappan civilisation

New Scientist - Gi, 26/11/2020 - 12:44
The Harappan lived 5200 years ago in the Indus valley in huge, complicated cities before their society eventually disappeared. Now it seems that two droughts in short succession may have caused their downfall
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